A Hybrid Heuristic Dimensionality Reduction Methods for Classifying Malaria Vector Gene Expression Data

dc.contributor.authorAROWOLO, MICHEAL O.
dc.contributor.authorADEBIYI, MARION OLUBUNMI
dc.contributor.authorADEBIYI, AYODELE ARIYO
dc.date.accessioned2023-08-31T16:10:00Z
dc.date.available2023-08-31T16:10:00Z
dc.date.issued2020-10-02
dc.description.abstractMalaria is the world’s leading cause of death, spread by Anopheles mosquitoes. Gene expression is a fundamental level where the effects of unseen vital revealing genes and developmental systems can be evident for detection of distinctions in malaria infections, to recognize the biological processes in human. Ribonucleic acid sequencing offers a large-scale measurable generated profiling transcriptional data results that help a variety of applications such as scientific and clinical condition studies. A fundamental limitation of ribonucleic acid sequencing consists of high dimensional, infrequent and noises, making classification of genes challenging. Several approaches have proposed enhancing the problem of the curse of dimensionality problem, requiring more improvement, yet it is critical to obtain accurate results. In this study, a hybrid dimensionality reduction technique proposes an optimized Genetic algorithm to pick pertinent subset features from the data. Features chosen is passed into principal component analysis and independent component analysis methods grounded on their class variants, to help transform the selected elements into a lower dimension separately. Support vector machine kernel classifiers used the reduced malaria vector dataset to assess the classification performance of the experimenten_US
dc.description.sponsorshipACE: Applied Informatics and Communicationen_US
dc.identifier.issn2169-3536
dc.identifier.urihttp://hdl.handle.net/123456789/2111
dc.language.isoenen_US
dc.publisherIEEE Accessen_US
dc.relation.ispartofseriesIEEE Access;VOLUME 8, 2020
dc.subjectGenetic algorithmen_US
dc.subjectprincipal component analysisen_US
dc.subjectindependent component analysisen_US
dc.subjectsupport vector machineen_US
dc.subjecthybrid approachen_US
dc.subjectRNA-sequencingen_US
dc.subjectNigeriaen_US
dc.subjectACE: Applied Informatics and Communicationen_US
dc.subjectCovenant Universityen_US
dc.subjectDigital Developmenten_US
dc.titleA Hybrid Heuristic Dimensionality Reduction Methods for Classifying Malaria Vector Gene Expression Dataen_US
dc.typeArticleen_US
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