Seminal Plasma concentrations of Semenogelin and Zinc Among infertile males and their association with Asthenozoospermia.

Simple item page
dc.contributor.authorMorokeji, Muyiwa Adeleye
dc.contributor.authorEmokpae, Mathias Abiodun
dc.date.accessioned2023-06-05T10:40:07Z
dc.date.available2023-06-05T10:40:07Z
dc.date.issued2020
dc.description.abstractPoor semen liquefaction is one of the causes of male infertility which has become a public health challenge in Nigeria. Abnormal sperm motility is one of the commonest abnormalities detected in infertile males. The pathogenesis of poor liquefaction and solidification of semen are modulated by Semenogelin and some other secretions from male accessory organs. To evaluate the concentrations of Semenogelin and zinc in seminal plasma and to correlate the levels with percentage sperm motility. Four hundred men, mean age 36.4±6.8 years who were evaluated for infertility and 100 men, mean age 40.2±6.6 years of proven fertility were consecutively recruited for the study. Following routine semen analysis, seminal plasma Semenogelin-1 and zinc were determined by ELISA technique and Atomic Absorption spectrophotometry techniques respectively. Data generated were compared between groups and association between Semenogelin, zinc and percentage sperm motility was determined. Seminal plasma Semenogelin level was higher (p<0.001) in infertile males irrespective of the sperm concentration than controls. On the other hand, seminal plasma zinc level was lower (p<0.001) among oligozoospermia and azoospermia than controls. The mean Semenogelin level was significantly higher (p<0.001) among asthenozoospermia than those with normal percent motility while mean seminal plasma zinc level in asthenozoospermia was lower (p<0.001) than those with normal percentage motility. Seminal plasma Semenogelin (R=-0.217; p<0.005) correlated negatively with asthenozoospermia and zinc (R=-0.148;p<0.05) but zinc correlated (R-0.150;p<0.05) positively with asthenozoospermia. Alterations in the levels of Semenogelin and zinc are associated with asthenozoospermia among infertile males.en_US
dc.description.sponsorshipACE: Reproductive Health Innovationen_US
dc.identifier.citationEmokpae MA et al., Seminal Plasma concentrations of Semenogelin and Zinc Among infertile males and their association with Asthenozoospermia.. British Journal of Medical and Health Research 2020.en_US
dc.identifier.issn2394-2967
dc.identifier.urihttp://hdl.handle.net/123456789/1906
dc.language.isoenen_US
dc.publisherBJMHR- British Journal of Medical and Health Researchen_US
dc.relation.ispartofseriesBr J Med Health Res.;2020;7(06)
dc.subjectACE: Reproductive Health Innovationen_US
dc.subjectNigeriaen_US
dc.subjectCERHIen_US
dc.subjectUniversity of Beninen_US
dc.subjectReproductive Healthen_US
dc.subjectMale Infertilityen_US
dc.subjectSperm Motilityen_US
dc.subjectSemenogelinen_US
dc.subjectZincen_US
dc.titleSeminal Plasma concentrations of Semenogelin and Zinc Among infertile males and their association with Asthenozoospermia.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Seminal Plasma concentrations of Semenogelin.pdf
Size:
197.45 KB
Format:
Adobe Portable Document Format
Description:
Main Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Health