Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology

Simple item page
dc.contributor.authorEgbuna, Chukwuebuka
dc.contributor.authorParmar, Vijaykumar K.
dc.contributor.authorJeevanandam, Jaison
dc.date.accessioned2023-05-17T10:43:36Z
dc.date.available2023-05-17T10:43:36Z
dc.date.issued2021-07-30
dc.description.abstractNanoparticles are of great importance in development and research because of their application in industries and biomedicine. The development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target, compatibility, and functions. This review presents a comprehensive update on nanoparticles' toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. Recent studies have found that nanoparticles may cause serious health effects when exposed to the body through ingestion, inhalation, and skin contact without caution. The extent to which toxicity is induced depends on some properties, including the nature and size of the nanoparticle, the surface area, shape, aspect ratio, surface coating, crystallinity, dissolution, and agglomeration. In all, the general mechanisms by which it causes toxicity lie on its capability to initiate the formation of reactive species, cytotoxicity, genotoxicity, and neurotoxicity, among others.en_US
dc.description.sponsorshipACE: Public Health and Toxicological Researchen_US
dc.identifier.citationgbuna C, Parmar VK, Jeevanandam J, Ezzat SM, Patrick-Iwuanyanwu KC, Adetunji CO, Khan J, Onyeike EN, Uche CZ, Akram M, Ibrahim MS, El Mahdy NM, Awuchi CG, Saravanan K, Tijjani H, Odoh UE, Messaoudi M, Ifemeje JC, Olisah MC, Ezeofor NJ, Chikwendu CJ, Ibeabuchi CG. Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology. J Toxicol. 2021 Jul 30;2021:9954443. doi: 10.1155/2021/9954443. PMID: 34422042; PMCID: PMC8376461.en_US
dc.identifier.issn1687-8191
dc.identifier.issn1687-8205
dc.identifier.urihttp://hdl.handle.net/123456789/1791
dc.language.isoenen_US
dc.publisherJournal of Toxicologyen_US
dc.relation.ispartofseriesJournal of Toxicology;Volume 2021
dc.subjectShahira M. Ezzaten_US
dc.subjectKingsley C. Patrick-Iwuanyanwuen_US
dc.subjectNanoparticlesen_US
dc.subjectingestionen_US
dc.subjectinhalationen_US
dc.subjectinhalationen_US
dc.subjectACE: Public Health and Toxicological Researchen_US
dc.subjectACE-PUTORen_US
dc.subjectUniversity of Port Harcourten_US
dc.subjectUniversity of Port Harcourten_US
dc.subjectNigeriaen_US
dc.titleToxicity of Nanoparticles in Biomedical Application: Nanotoxicologyen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Toxicity of Nanoparticles.pdf
Size:
1.26 MB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Health