Potential of laser-induced fluorescence-light detection and ranging for future stand-off virus surveillance

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dc.contributor.authorOwoicho, Oloche
dc.contributor.authorOchieng, Charles
dc.contributor.authorOlwal, Charles Ochieng’
dc.contributor.authorQuaye, Osbourne
dc.date.accessioned2023-04-26T15:51:08Z
dc.date.available2023-04-26T15:51:08Z
dc.date.issued2020-11-26
dc.description.abstractViruses remain a significant public health concern worldwide. Recently, humanity has faced deadly viral infections, including Zika, Ebola and the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The threat is associated with the ability of the viruses to mutate frequently and adapt to different hosts. Thus, there is the need for robust detection and classification of emerging virus strains to ensure that humanity is prepared in terms of vaccine and drug developments. A point or stand-off biosensor that can detect and classify viruses from indoor and outdoor environments would be suited for viral surveillance. Light detection and ranging (LiDAR) is a facile and versatile tool that has been explored for stand-off detection in different environments including atmospheric, oceans and forest sensing. Notably, laser-induced fluorescence-light detection and ranging (LIF-LiDAR) has been used to identify MS2 bacteriophage on artificially contaminated surgical equipment or released amidst other primary biological aerosol particles in laboratory-like close chamber. It has also been shown to distinguish between different picornaviruses. Currently, the potentials of the LIF-LiDAR technology for real-time stand-off surveillance of pathogenic viruses in indoor and outdoor environments have not been assessed. Considering the increasing applications of LIF-LiDAR for potential microbial pathogens detection and classification, and the need for more robust tools for viral surveillance at safe distance, we critically evaluate the prospects and challenges of LIFLiDAR technology for real-time stand-off detection and classification of potentially pathogenic viruses in various environments.en_US
dc.description.sponsorshipACE: Cell Biology of Infectious and Non-Communicable Diseasesen_US
dc.identifier.citationhttps://doi.org/10.1111/1751-7915.13698en_US
dc.identifier.issn1751-7915
dc.identifier.urihttp://hdl.handle.net/123456789/1593
dc.language.isoenen_US
dc.publisherJohn Wiley & Sons Ltd and Society for Applied Microbiologyen_US
dc.relation.ispartofseriesMicrobial Biotechnology;(2021) 14
dc.subjectlaser-induceden_US
dc.subjectfluorescence-lighten_US
dc.subjectLIFLiDAR technologyen_US
dc.subjectUniversity of Ghanaen_US
dc.subjectWACCBIP_NCDSen_US
dc.subjectACE: Cell Biology of Infectious and Non-Communicable Diseasesen_US
dc.titlePotential of laser-induced fluorescence-light detection and ranging for future stand-off virus surveillanceen_US
dc.typeArticleen_US
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