Lapidus, SarahLiu, FeimeiCasanovas-Massana, Arnau2023-06-092023-06-0920212475-9066http://hdl.handle.net/123456789/1936Individuals with acute malaria infection generated high levels of antibodies that cross-react with the SARS-CoV-2 Spike protein. Cross-reactive antibodies specifically recognized the sialic acid moiety on N-linked glycans of the Spike protein and do not neutralize in vitro SARS-CoV-2. Sero-surveillance is critical for monitoring and projecting disease burden and risk during the pandemic; however, routine use of Spike protein-based assays may overestimate SARS-CoV-2 exposure and population-level immunity in malaria-endemic countriesenYile DaJohn D. HucCarolina LucasPlasmodiumACE: Bio-technological Innovation for the Elimination of Vector- Borne DiseasesUniversité Nazi BoniCEA-ITECH_MTVPlasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein