x, 113p. :ill.The purpose of this research was to find out the factors affecting female enrolment in basic schools in the Twifo Hemang Lower Denkyira District. Using the District as the case study. A total of 150 parents, 100 teachers and 150 dropout girls formed the accessible population. Within a period of two months, the researcher and his two assistants interviewed all the 400 respondents. Data collected were analysed manually and electronically by using descriptive statistical tools such as simple frequencies, relative frequencies and percentages. At the end of the study it came to light that many parents could not enroll or support their daughters' education due to poverty. Again, it was found that non-literate parents, especially, those in the rural communities had negative attitude towards female education. Based on the findings a number of conclusions were drawn and recommendations made on certain important factors to be considered for the necessary remedial measures to be instituted and implemented to better enrollment of girls in the basic schools in the Twifo Hemang Lower Denkyira District. Specifically, it was recommended that women groups should assist girls with their basic school amenities so that it would enhance girls' enrollment in the basic school in the district. In the same light, educated females from the district should team up with female teachers to mentor girls so that they would strive to remain in school because the benefits that would accrue from schooling are numerous.