The CircumVent Project: a CPAP/O2 helmet solution for non-invasive ventilation using an implementation research framework

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dc.contributor.author. Ahonkhai, Aimalohi A
dc.contributor.authorMusa, Adesola Z.
dc.contributor.authorFenton, André A.
dc.date.accessioned2023-05-10T18:12:56Z
dc.date.available2023-05-10T18:12:56Z
dc.date.issued2021-08-26
dc.description.abstractBackground: Acute respiratory failure, a major cause of death in COVID-19, is managed with high-flow oxygen therapy via invasive mechanical ventilation. In resource-limited settings like Nigeria, the shortage of ventilators and oxygen supply makes this option challenging. Evidence-based non-invasive alternatives to mechanical ventilation such as the use of continuous positive airway pressure (CPAP) devices exist, but there have been concerns that non-invasive ventilation may expose healthcare workers to infection from aerosolized dispersion of SARS-CoV-2. We propose to evaluate the feasibility, adaptability and acceptability of a CPAP/O2 helmet solution for non-invasive ventilation among patients with COVID-19 and health workers in eight COVID-19 treatment and isolation centers in Nigeria. Methods: The study will occur in 4 stages: (1) convene a Steering Committee of key stakeholders and recruit implementation sites; (2) use the integrated Promoting Action on Research Implementation in Health Services (i-PARiHS) framework to guide a needs assessment of treatment centers’ capacity to use high-flow oxygen therapy to treat COVID19 patients and utilize the findings to develop an implementation strategy for the use of a CPAP/O2 helmet solution; (3) build infrastructure to support training and data monitoring processes and to develop implementation protocols to evaluate the adaptability of the strategy for the use of the CPAP/O2 helmet; and (4) train health workers, distribute a CPAP/O2 helmet solution for non-invasive ventilation, pilot test the implementation strategy, and assess feasibility of its use and acceptability that includes monitoring altered risk of SARS-CoV-2 infection among healthcare workers. Discussion: The CPAP/O2 helmet solution for non-invasive ventilation in Nigeria can serve as a scalable model for resource-poor countries, and beyond the COVID-19 pandemic, has the potential to be deployed for the treatment of pneumonia and other respiratory diseasesen_US
dc.description.sponsorshipACE: Population Health and Policyen_US
dc.identifier.issn 2662-2211
dc.identifier.urihttp://hdl.handle.net/123456789/1766
dc.language.isoenen_US
dc.publisherSpinger Natureen_US
dc.relation.ispartofseriesImplementation Science Communications;2021) 2:93
dc.subjectSARS-CoV-2en_US
dc.subjectCOVID-19 infectionen_US
dc.subjectNigeriaen_US
dc.subjectNon-invasive ventilationen_US
dc.subjectImplementation scienceen_US
dc.subjectACEPHAPen_US
dc.subjectACE: Population Health and Policyen_US
dc.subjectACE: Population Health and Policyen_US
dc.titleThe CircumVent Project: a CPAP/O2 helmet solution for non-invasive ventilation using an implementation research frameworken_US
dc.typeArticleen_US
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